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They have exhibited a wide variety of biological activities for thousands of years, including targeting mitochondrial dysfunction ( 2 Mitochondrial dysfunctions in kidney diseases 2.1 Mitochondrial homeostasis imbalance Mitochondrial quality control (MQC) is an elaborate mechanism to maintain homeostasis, ensuring the enough numbers of functional mitochondria (Figure 1)

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This process helps the body eliminate free radicals and toxins generated by cancer or its treatments

Besides succinic acid, we identified two additional differential metabolites: glyoxylate and xanthine

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