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Retatrutide is an investigational injectable medicine being developed primarily for the treatment of obesity and type 2 diabetes

Wu W, Ding D, Zhao Q, et al

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Some insurers require documented trial of oral supplementation before approving injections, though this contradicts the pathophysiology-patients with true intrinsic factor deficiency cannot absorb oral B12 regardless of dose

The patient underwent FMT infusion with material from five healthy donors and was followed for 12 months for clinical assessments, detailed descriptions of fecal microbiome composition, fecal SCFA concentration measures, and serum levels of inflammatory and neuroprotective biomarkers (Engen et al., 2020)