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observed that flavonoids eliminated the superoxide peroxynitrite, and they additionally found that rutin and epicatechin are prominent radical scavengers due to their ability to inhibit xanthine oxidase [205]

doi: 10.1016/j.ebiom.2022.104258 43 DollSFreitasFPShahRAldrovandiMda SilvaMCIngoldIet al

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Moreover, TB-500 also appeared to have promoted the expression of CD31, -smooth muscle actin (-SMA), Ang2, tie2, VEGFA, N1ICD, and p-p65 in the muscle tissues of murine CLI models