(The Cochrane Collaboration) (July 21, 2003)
It has been hypothesized that a reduction in deuterium levels in the sugar-phosphates in the DNA backbone preserves the stability of hydrogen bond networks, protecting against aneuploidy and strand breaks ( Exposure of cells to deuterium-hydrogen ratios that differ from the natural ratio of 1/6600 alter the expression of hundreds of cancer-related and kinase genes, reflecting the fact that deuterium levels play a significant role in metabolic policy
In some cases, dimers may direct the formation of higher order oligomers, such as, for example, in the case of epsin 1 (Yoon et al., 2010
This prompted the development and investigation of safer derivatives
Perkins S, Verschoyle RD, Hill K, Parveen I, Threadgill MD, Sharma RA, et al