what happens when glutathione increases in Skin Aging and Tissue Regeneration: A Systematic Review of Molecular Mechanisms, Redox Modulation, and Biomedical Implications The Role of Glutathione Metabolism

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Omran and Omer 2015

The risk variant PTPN22 (R620W) encodes a hyperactive phosphatase that paradoxically attenuates T-cell receptor signaling, leading to aberrant thymic selection and escape of autoreactive lymphocytes

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