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This is true for both oral supplements and injections, backed by clinical evidence

Among these metal-based NPs, only CuO NPs caused oxidative stress by significantly increasing intracellular ROS (Karlsson et al., 2008)

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Research suggests that those with autoimmune diseases lack optimal antioxidant function

N-acetylcysteine, or NAC, is a supplement that works in two ways: It provides cysteine, which is the rate-limiting amino acid for glutathione production It can also act as a direct antioxidant to scavenge ROS (NO2 and HOX)[ref][ref] The main antioxidant mechanism for NAC is by increasing glutathione levels