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In a prospective, casecontrol study in an Australian population, mean serum selenium decreased in parallel with increasing severity of Graves orbitopathy: 940 (sd 158) g/l in GD, 869 (sd 150) g/l in moderate-to-severe Graves orbitopathy and 861 (sd 13.4) g/l in sight-threatening Graves orbitopathy ( P = 0003) ( Reference Khong, Goldstein and Sanders 84 )

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No additional antioxidants, no liposomal wrapping, no sustained-release matrix

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