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Xie et al., 2024)

Tests involving multiple factors were analyzed using either a three-way analysis of variance (ANOVA) with diet, time, and sex as variables, a two-way ANOVA with diet and time as variables, followed by Sidaks post hoc test, a two-way repeated measures (RM) ANOVA for longitudinal data, followed by Dunnetts post hoc test or by one-way ANOVA followed by Tukeys post hoc test as specified in the figure legends

This gene-environment interaction not only provides new insights for depression prevention and intervention but also forms the basis for developing personalized treatment strategies

Histone H1 recruitment by CHD8 is essential for suppression of the Wnt-beta-catenin signaling pathway

Moreover, loss-of-function mutations of succinate dehydrogenase (SDH) increase cellular succinate level, which inhibits DNA demethylation and contribute to tumorigenesis [62,63]