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Despite such limitations, our exploration nevertheless confirmed NACs safety in long-term high-dose administration during pregnancy

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Therefore, a key question is whether certain individuals have an inflection point for clinically important paracetamol toxicity at a dose within or close to the recommended therapeutic dose

One mechanism that contributes to cytochrome c detachment from IMM involves cardiolipin oxidation because oxidized cardiolipin has a much lower affinity for cytochrome c than the reduced form