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PFKFB3 modulates glycolytic metabolism and alleviates endoplasmic reticulum stress in human osteoarthritis cartilage

Owing to its lipid composition, which closely resembles human sebum, crocodilian oil demonstrates excellent dermal compatibility, with no reported cases of irritation or allergic reactions

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Nevertheless, it is unclear whether IGF promotes cell proliferation directly via the IGF receptors expressed in them or whether it occurs indirectly by triggering granulosa cell-secreted secondary growth factors, thereby influencing the theca cells directly [10, 11]