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What is more, the vitamin B12 forms we have discussed above do not work alone in the body, but are part of a large complex of B vitamins and operate in combination with a number of other vitamins and minerals

In the centrilobular hepatocytes, there was substantial proliferation of rough endoplasmic reticulum, as shown by electron microscopy with slightly less than half of the periportal hepatocytes showing rough endoplasmic reticulum proliferation

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doi:10.1038/273120a0

If its not perfectly clear, it should not be used