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Glutamine is catabolized by different enzymes, including GLS, CAD, or glutamine fructose 6 phosphate aminotransferase (GFAT)

Overexpression of AtHsp90.3 in Arabidopsis thaliana impairs plant tolerance to heavy metal stress

(235), and its decreased content may cause higher oxidative stress in the thyroid (235)

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What the animal studies cannot tell us includes optimal human dosing, population-specific responses (elderly, children, pregnancy), long-term safety in humans, rare side effects that require large sample sizes to detect, and interactions with medications or medical conditions