Materials Science & Engineering A Structural Materials Properties Microstructure and Processing, 795 , Article 139993
PubMed 22962027 TB-4 Phase 1 human safety first-in-human randomized, double-blind, single- and multiple-dose Phase 1 of recombinant human thymosin 4 in healthy volunteers, no serious adverse events: PubMed 34346165
Treatment parameters are adjusted based on the type of neck injury and pain pattern
Thymosin beta-4 is the most abundant G-actin sequestering peptide in mammalian cells, maintaining the pool of unpolymerised actin monomers available for cytoskeletal dynamics, and was originally identified as a thymic hormone before its much broader roles in wound healing, angiogenesis, cell migration, anti-inflammatory biology, and tissue regeneration were characterised
Saline adds a different problem: the sodium chloride can interact with some peptide chemistries and provides no bacteriostatic activity