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Targeted expression, purification, and cleavage of fusion proteins from inclusion bodies in Escherichia coli

The authors reported that AOD-9604 stimulated lipolysis in isolated adipocytes and that chronic daily treatment in obese Zucker rats produced reductions in body weight gain of more than 50% relative to untreated controls over the treatment period, without effects on insulin sensitivity or IGF-1 levels [3]

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These detrimental effects are further exacerbated by a marked decline in sperm vitality, resulting from plasma membrane peroxidation and loss of membrane integrity