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A systematic review and meta-analysis by Bray and colleagues assessed the effects of GLP-1RAs on biomarkers of inflammation and oxidative stress in individuals with T2DM, and reported a significant reduction in CRP, TNF-, malondialdehyde, along with significant increases in adiponectin levels [96]

PMID: 2323674

Neurobiol Stress (2015) 1:8999

133 It has been reported that inhibiting the mTOR signaling pathway with rapamycin enhanced both autophagy and NETs formation, while activating the mTOR signaling pathway with insulin suppressed both processes in neutrophils isolated from health donors

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