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The effects of NTZ were compared to those of the standard antioxidant, N-acetyl cysteine (NAC), as a well-documented hepatoprotective agent known to inhibit ER stress, and to those of 4-phenyl butyrate (4-PBA), a standard ER stress inhibitor ( 2 Materials and methods 2.1 The experimental animals Currently, we included 36 adult male albino Wistar rats (with a body mass range equal to 190230 g, 810 weeks of age) supplied by the Faculty of Veterinary Medicine, Zagazig University. Rats were kept in hygienic laboratory conditions, including temperature (22C 3C), relative humidity (60% 10%), and normal light/dark cycle

Genome Biol 2015;16:257

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For PDT, both IR820 and catalase were encapsulated in PLGA NPs to reach the MV3 melanoma cell line intravenously in the BALB/c nude mice at 68 weeks of age [196]