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Studies in cell culture have demonstrated that specific peptide sequences can upregulate procollagen synthesis in dermal fibroblasts, while others influence the activity of matrix metalloproteinases (MMPs) the enzymes responsible for collagen degradation and ECM remodelling

Cytogenetics and Cell Authentication Core facility was used and funded by the MD Anderson Cancer Center Support Grant, P30CA016672, from the National Institutes of Health/National Cancer Institute

This effect was dampened in aged Mda5 -/- bone marrow serum (Fig

Autophagy also influences ferroptosis by regulating SLC7A11

Furthermore, ScGrx8, which has an alanine residue at the same position (Fig