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It was hoped that the drug would offer improved weight loss for patients with diabetes, who typically have a tougher time shedding pounds on existing GLP-1 treatments, but the 15.7% weight reduction result from the REDEFINE-2 trial disappointed

Estimates suggest oral bioavailability for peptides like BPC-157 may be only 1-2%, meaning massive doses would be required to achieve systemic effects

Answer: The core benefit is durable appetite control without stimulants, which supports steady weight loss, easier portion control, and, when combined with a GLP-1 medication, weight loss outcomes that rival much more aggressive interventions in trials

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Gray-market peptides can create risks beyond the peptide itself, raising concerns over product quality, purity, and inconsistent formulation