The cardiovascular system is uniquely vulnerable to these dramatic metabolic shifts, which is particularly relevant for patients dealing with dysautonomia and postural orthostatic tachycardia syndrome (POTS)
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Andrade LM, Rocha KA, De S FA, Marreto RN, Lima EM, Gratieri T, et al
Suprachiasmatic nucleus in the mouse: Retinal innervation, intrinsic organization and efferent projections
Thus, the reaction is not coupled to energy production but instead yields a significant reactive oxygen species (ROS)