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Prolonged pharmacological inhibition of cathepsin C results in elimination of neutrophil serine proteases

While multiple compounds and approaches have been suggested in the preclinical setting as potential treatments for SCA3 [174, 178], little has translated to clinical studies, which is clear by the small number of interventional trials carried out so far

Genomic template stability is a crucial indicator of DNA integrity and it can be significantly affected by various environmental factors and chemical treatments [72]

PMID: 39275201

4d) revealed that the permeated amount of copper peptides was 2.65-fold higher after delivery using CaT than that using PBS, while it improved to 3.18-fold higher than that of the PBS group when using the CaT-ME system as the carrier