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Studies suggest it can block the NF-B pathway and reduce inflammatory cytokines like TNF- and IL-6 without causing skin darkening, making it a potentially safe option for systemic use

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Its protective and brightening benefits make glutathione a key ingredient in many anti-aging and skincare products

Spinal stenosis ranks as another frequent cause, particularly in adults over 50 this narrowing of the spinal canal puts pressure on the nerve endings that form the sciatic nerve