Significant alterations in the abundance of family Bacillaceae [61], increased relative abundance of genera Peptoniphilus and Finegoldia , and decreased relative abundance of genus Faecalibacterium and Ruminococcus gauvreauii were detected in PD patients treated with levodopa versus controls
Neurobiology of Aging 32 (5), 763777 (2011)
For example, in the mouse testis, CYP51A1 expression is primarily regulated by the cAMP-responsive element modulator tau (CREMtau), which drives a germ cell-specific increase in CYP51A1 mRNA levels during spermatogenesis
Similarly, the same dose of Mn was injected every 10 days for 150 days and also resulted in fewer TH-positive cells with impaired motor activity (Peres et al., 2016)
Beclin-1, a key protein in autophagy initiation, was reduced by 60% in DOX muscle compared to control, indicating impaired autophagic signaling