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Despite promising preclinical data, challenges such as poor bioavailability, dose-dependent safety concerns, and the need for large-scale randomized clinical trials and regulatory standardization remain

Its role is centered on healing, inflammation control, and tissue repair

Extracellular matrix remodelling and actin regulation studies

7 Environmental factors play a role in this system, with sensory information fed into the central clock through signals from the eye, which are then converted to chemical signals in the SCN and synchronized with the peripheral systems

Senolytic therapies like FOXO4-DRI may offer a promising approach to modulate aging and halt neurodegenerative disease progression (4)