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Oral Voxelotor (Oxbryta) inhibits HbS polymerization

10.1016/j.bmcl.2016.02.080 21 KangH

Vitamin B12 plays a central role in this process

Researchers arent claiming a finished story here

Early studies indicated that CHAC2 expression was not differentially regulated and was generally higher than that of CHAC1, suggesting a role in the basal turnover of GSH rather than the stress- and signaling-associated functions of CHAC1