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Intriguingly, emerging evidence suggests that some newer agents such as ocrelizumab (a B cell-depleting monoclonal antibody) and siponimod (a sphingosine 1-phosphate receptor modulator with anti-inflammatory and neuroprotective properties) are beneficial in progressive MS, potentially with effects independent of suppressing acute inflammation (Montalban et al., 2017
4.16 Statistics All normalized values were transferred to GraphPad Prism 8.4.3 for statistical analysis of biological replicates
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Physician supervision, baseline bloodwork, and structured cycling represent the minimum standard for responsible use
Best choice: your provider can recommend the right option based on your B12 level, the cause of your deficiency, and your symptoms
