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While blood flow and vascular transport of nutrients may play a role in heat-enhanced limb elongation (discussed in section 6), temperature may also directly alter growth through changes in IGF-1 expression

doi: 10.3389/fmicb.2024.1446595 Received 10 June 2024 Accepted 02 August 2024 Published 14 August 2024 Volume 15 - 2024 Edited by Daniela De Biase, Sapienza University of Rome, Italy Reviewed by Wolfgang Buckel, University of Marburg, Germany Malte Sinn, University of Konstanz, Germany Updates Copyright 2024 Piskol, Lukat, Kaufhold, Heger, Blankenfeldt, Jahn and Moser

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In addition, whatever the initial infectious agent, an inflamed, damaged gut mucosa allows microbial translocation, accompanied by the release of the bacterial and inflammatory endotoxin LPS