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Disruptions in this axis, driven by gut dysbiosis, have been implicated in the pathogenesis of a wide range of neurodegenerative and neuropsychiatric disorders

The clinical application of alpha-lipoic acid in metabolic dysfunction-associated steatotic liver disease Metabolic Dysfunction-associated Steatotic Liver Disease is a chronic liver disease characterized by excessive fat accumulation in the liver, insulin resistance, oxidative stress and inflammatory responses, which can progress to non-alcoholic steatohepatitis, fibrosis, cirrhosis and even hepatocellular carcinoma

Glucose regulated protein 94 is required for muscle differentiation through its control of the autocrine production of insulinlike growth factors

doi:10.1517/17425247.2012.735658

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