Along the same lines as ivacaftor and hypertonic saline, several pharmaceutical groups have been pursuing pharmaceuticals that target other ion channels to improve mucociliary clearance in a cftr -independent manner
Reis SE, Gloth ST, Blumenthal RS, Resar JR, Zacur HA, et al
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Abstract Due to their rapid and uncontrolled proliferation, cancer cells are characterized by overexpression of glutathione (GSH), which impairs reactive oxygen species (ROS)-based therapy and weakens the chemotherapeutic agent-induced toxification
12 DomenechM.Ramos-SevillanoE.GarcaE.MoscosoM.YusteJ