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Expert Opinion on Therapeutic Patents, 31(5), 401414

Xuemei Tao, [email protected] These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Similar content being viewed by others Introduction Statins lower blood plasma cholesterol by inhibition of 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase (HMG-CoA-R), which converts HMG-CoA to mevalonic acid, an early step in the mevalonate pathway that produces cholesterol and isoprenoids