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English search terms included: diabetic kidney disease OR diabetic nephropathy OR DKD OR DN, combined with gut microbiota OR gut microbiome OR intestinal flora OR intestinal microbiota, dietary OR nutrition OR diet OR nutritional intervention, phytochemical OR natural product OR bioactive compound OR functional food, amino acid metabolism OR metabolite OR metabolomics, gut-liver axis OR gut-kidney axis OR enterohepatic axis, short-chain fatty acids OR SCFAs, and probiotics OR prebiotics OR synbiotics. Inclusion criteria were: (1) studies addressing the associations among DKD, gut microbiota, nutritional intervention, and natural bioactive compounds

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One of the tests may include an intravesical potassium sensitivity test which is based on the theory that abnormally permeable urothelium allows diffusion of potassium into the bladder wall

After 20 minutes, the upper aqueous layer is collected