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Each time, vary the injection site (alternate legs, for instance) to prevent soreness or muscle irritation

The lyophilized powder should be stored at -20C prior to reconstitution with sterile water or bacteriostatic water

Blood tests, physical exams and EKGs are not able to detect it

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Rectal administration (infliximab), tablet coating (V565-adalimumab), anti-TNF- loaded nanoparticles [185,186,187], avian polyclonal anti-TNF-, antisense oligonucleotides in several formulations, intracolonic microRNA and per os- or rectal-administered small interfering RNA that silence TNF- expression, have been studied with varying efficacy [183]