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Mutations conferring GSH-independence map to the protomer interface between proteins VP1 and VP3 and are consistent with GSH binding being essential for the formation of pentameric subunits critical to assembly 24,27

In metabolically demanding retinal cells, healthy mitochondria essential for sustaining cellular functions and preventing energy-depletion-induced cell death

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From a pharmacokinetic perspective, studies indicate no evidence that the combination of Vitamins B1, B6, and B12 adversely affects the pharmacokinetics of each individual vitamin

Phenotype of the obese Koletsky (f) rat due to Tyr763Stop mutation in the extracellular domain of the leptin receptor (Lepr): evidence for deficient plasma-to-CSF transport of leptin in both the Zucker and Koletsky obese rat