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Change history 21 September 2025 The original online version of this article was revised due to the figures 1, 2, 3 have been printed with a black background
Even-Toned Skin : The strategic reduction of dark spots and hyperpigmentation gives you a more uniform skin tone
Talk with a licensed provider before starting or stopping any medication or supplement
Though the evidence base is limited to a small number of case reports, those with known cobalt allergy are advised to discuss B12 supplementation with a clinician before starting (MHRA, 2023)
Dosing protocols Phase 2 clinical trials used a titration schedule starting at 0.5mg weekly, escalating through 1mg, 2mg, 4mg, 8mg, and reaching maintenance doses of up to 12mg weekly over several months
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