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Deutsch SI, Burket JA (2020) An evolving therapeutic rationale for targeting the 7 nicotinic acetylcholine receptor in autism spectrum disorder

In Drosophila and mammalian systems alike, clock proteins such as PER, tim, and CRY are rhythmically ubiquitinated and degraded, a process that defines the length of the circadian period by delaying or advancing the feedback inhibition phase (Vriend and Reiter, 2015

PMCID: PMC8345998

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Classified as a pentadecapeptide (15 amino acids), it functions as a signaling molecule in experimental models rather than an approved medical treatment