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1 Introduction The phenomenon of aging is characterized by a gradual deterioration in skeletal muscle mass, strength, and functional capacity, a pathological state referred to as sarcopenia, which plays a substantial role in the development of frailty, metabolic impairment, and the erosion of autonomy among elderly populations

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Another strategy is utilizing PARP inhibitors, which resulted in rescuing NAD + levels and decreasing A aggregation in brain samples of AD flies, however, this study did not include any measurements of mitochondrial function 275

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