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In case you didnt know, anxiety and depression are often triggers for weight gain, so theres yet another reason to look out for vitamin deficiencies when youre struggling with weight loss
Additionally, the microbiomes in these treatment groups were compared to both age-matched lean and obese controls
Therefore, it shouldnt surprise you that it takes a lot more than a day or two to fix a deficiency and correct its resulting anemia
Requirements of vitamin B12 in excess of normal (due to pregnancy, thyrotoxicosis, hemolytic anemia, hemorrhage, malignancy, hepatic and renal disease) can usually be met with oral supplementation
Nevertheless, use of metformin may decrease vitamin B 12 status: a meta-analysis of four short-term intervention trials (up to 4 months duration) in patients with type 2 diabetes found that metformin use decreased serum cobalamin concentrations by 57 pmol/L, which could have clinical implications if such patients have suboptimal vitamin B 12 status (146)
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