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A proposed role in ascorbic acid metabolism

Methylation is important because the presence of methyl groups on a molecule can block or encourage certain chemical reactions, functioning as a switch with the potential to turn a biological process on or off

On the other hand, we have found that EqASCEMS treated with SHBG are characterized by lower polarization of mitochondrial membrane which justified the enhanced proliferative ability of EqASCEMS when treated with SHBG

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Because KLRG1 is widely used as a marker of highly activated, cytokine-producing ILC2s (66, 67), this finding supports the idea that melatonin drives a phenotypic transition from an activated, KLRG1 high effector state toward a more quiescent, KLRG1 low phenotype