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An elevated ratio may indicate either a production excess or, in the case of LR3 use, artificially reduced binding capacity

Borchert A, Kalms J, Roth SR, Rademacher M, Schmidt A, Holzhutter H-G et al (2018) Crystal structure and functional characterization of selenocysteine-containing glutathione peroxidase 4 suggests an alternative mechanism of peroxide reduction

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A novel CpG island set identifies tissue-specific methylation at developmental gene loci