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Curr Drug Metab 2001

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Piya S, Yang Y, Bhattacharya S, Mu H, Ruvolo V, Baran N, Davis RE, Qian Y, You MJ, Konopleva M, Kantarjian H, Andreeff M , Borthakur G

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10.1038/tp.2013.91 Transl

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The key lesson from ACE-031 was that broad TGF-beta superfamily inhibition produces unacceptable off-target effects, particularly vascular toxicity

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