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Most likely yes, if the ambient temperature was below 86 degrees Fahrenheit and the total room temperature exposure time (including this incident) has not exceeded 21 days

The deterioration of the quality and quantity of mtDNA is significantly important to mitochondrial dysfunction during aging

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doi: 10.1210/jc.2018-00953

Moreover, the timing of differentiation, seeding, and maturation must often be finely tuned to ensure appropriate cellular organization and function, especially in systems that mimic tissue development or disease progression