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Nanomolar concentrations of caudatin can induce the production of reactive oxygen species, which represents an important upstream event in activating the apoptotic machinery associated with caudatin

Ray SD, Lam TS, Rotollo JA, Phadke S, Patel C, Dontabhaktuni A, Mohammad S, Lee H, Strika S, Dobrogowska A, Bruculeri C, Chou A, Patel S, Patel R, Manolas T, Stohs S

It was shown before that supplementation with Ferrostain-1 (FER1), which suppresses the accumulation of lipid hydroperoxides in a catalytic fashion 41 , inhibited cell death induced by RSL3 treatment 13

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[121] After the IF/B 12 complex binds to cubam the complex is disassociated and the free vitamin is transported into the portal circulation