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The researchers proposed that the senolytic effect observed in these cells is attributable not only to the disruption of the PI3K/AKT pathway but also to interference with the ERK/MEP pathway, which plays a crucial role in regulating inflammation and resistance to apoptosis [123]

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10.1371/journal.pone.0057226 35 Mller-RverS.HandjiskiB.van der VeenC.EichmllerS.FoitzikK.McKayI

Overall, MSM alleviates pathogen- and stress-induced physiological disorders in poultry primarily by modulating inflammatory signaling and enhancing antioxidant defenses, although its efficacy may vary depending on the disease-specific contexts