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Monomethyl auristatin E HY-P9907 It is implicated in the

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Description

It is implicated in the regulation of tumor cell growth

eliminating the need for a Dounce homogenizer and ultracentrifugation

Traditional methods for isolating the Golgi apparatus rely on density gradient ultracentrifugation

leading to subsequent fusion with the plasma membrane

Cell extracts and supernatants were separated by SDS-PAGE under reducing conditions

Monomethyl auristatin E HY-P9907 It is implicated in theMonomethyl auristatin E (MMAE; SGD 1010) is a synthetic derivative of dolastatin 10 and functions as a potent mitotic inhibitor by inhibiting tubulin polymerization. MMAE is widely used as a cytotoxic component of antibody drug conjugates (ADCs) to treat several different cancer types.

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