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Therefore, measuring GSH levels to determine the availability of cysteine as the limiting step must be considered in future studies

Metformin, commonly prescribed for type 2 diabetes, is known to reduce B12 absorption over time, as highlighted in MHRA safety updates

The delay in worsening functions followed the same dose-dependent trend

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Intestinal Barrier Dysfunction: Preclinical evidence suggests that by lowering systemic oxidative stress, NAC may promote intestinal barrier integrity and support a healthy balance of intestinal microbiota, addressing the gut dysbiosis often seen in chronic illness