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The side-chain guanidyl group of Arg454 interacts with the carboxylate moiety of glycine to orient the substrate for attack on the acyl-phosphate intermediate (Herrera et al., Unlike other organisms, some plants synthesize glutathione analogs in which -alanine, serine, or glutamate replaces glycine in the tripeptide (Figure 4A)

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Long-term follow-up indicated that a minority required ongoing therapy or experienced relapse, although such instances were uncommon

Lyophilized (freeze-dried) peptide remains stable for extended periods at room temperature or longer when refrigerated

Contains the goodness of glutathione and papaya extracts