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Undigested food particles and toxins may escape into the bloodstream, triggering inflammation throughout the body

Changes in the prevalence of cognitive impairment among older Americans, 19932004: Overall trends and differences by race/ethnicity

Such integrative approaches reveal how dynamic metabolic remodeling within the TMEincluding hypoxia, nutrient deprivation, and immunosuppressive metabolite accumulationreshapes immune cell states and fosters therapeutic resistance

In addition, Yang et al

The brain changes of Alzheimer's disease include the excessive accumulation of the protein fragment betaamyloid and of an abnormal form of the protein tau