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Beyond TSHR, IGF-1R has been implicated in TAO pathogenesis due to its crosstalk with TSHR [298, 341,342,343,344]

Accessed on 24th April, 2025

It is a skin-identical ingredient, it is probably moisturizing and anti-inflammatory but its topical effects are less established than that of fellow omega fatty acid, linoleic acid

Data Availability All data and information used in the preparation of this review article are cited in the references and are accessible to readers (open access)

Dosing and timing may depend on health history, lab work, treatment goals, medication use, response to treatment, cycle length, and safety risks