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ACKNOWLEDGMENTS FOR REPLICATION SAMPLES Childrens Hospital of Philadelphia/Price Foundation: We gratefully thank all the patients and their families who were enrolled in this study, as well as all the control subjects who donated blood samples to Childrens Hospital of Philadelphia (CHOP) for genetic research purposes

Disclosure of interest: There are no relevant conflicts of interest

Discard any vial that is past the 3-month BUD or shows signs of contamination.

These ampoules provide a convenient and effective way to replenish B12 levels where deficiency is present