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Albrech J, Talbot M, Kimelberg HK, Ascher M

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doi: 10.3402/jom.v6.22993 148 SomerA.TorunS

Monitoring glutathione status in biopharmaceutical production or food processing pipelines provides a robust quality marker for ensuring batch-to-batch consistency and detecting oxidative degradation

For instance, disruption of circadian rhythms by repeated advances in the light-dark schedule in rodent models consistently altered expression of core clock genes such as Per2 and Bmal1, leading to impaired immune function, including reduced NK cell cytotoxicity and decreased expression of cytolytic factors like IFN, perforin, and granzyme B