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Moreover, when moderately induced by a 100 ng/ml doxycycline, these two mutations resulted in reduced GM130-LYSET colocalization and mislocalization of some LYSET to the plasma membrane in SKMEL30 cells (Fig

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In vivo studies confirmed that HKDC1 knockdown significantly suppressed peritoneal metastasis of AGS cells in mice, as demonstrated by bioluminescence imaging and increased metastatic nodule counts (Fig

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